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Vitiligo is a depigmentation or reduction of skin, mainly due to the massive loss of melanocytes
.
Due to its impact on appearance, vitiligo will seriously affect the quality of life of patients and increase the psychological burden of patients
At present, the main treatment for vitiligo is a combination of phototherapy and topical anti-inflammatory drugs
.
For those patients who do not respond to treatment, autologous cell transplantation is considered a good option
Recently, a randomized study published in Acta Derm Venereol evaluated non-cultured autologous epidermal cell transplantation resuspended in hyaluronic acid vs.
Hyaluronic acid alone (neutral comparison agent), 6 months later for vitiligo and alopecia areata The effect of re-pigmentation of lesions
.
Each patient included in the study has two definite paired lesions, which are randomly assigned to any one device for treatment
.
The equipment with ready-to-use kits is prepared by different health professionals to maintain blindness
As a result, of the 38 patients screened, 36 (94.
7%) patients entered the final study analysis, which is equivalent to 72 lesions
.
For difficult-to-treat lesions, defined as lesions located in the wrists, elbows, and hands (n = 30), no repigmentation of ≥50% was observed
In summary, the results of the study indicate that the single application of non-cultured epidermal cell transplantation using the ready-to-use kit is effective during the 6-month and 1-year follow-up
.
It is worth noting that this equipment does not require special facilities (cell culture) or hospitalization (surgery can be performed in an outpatient clinic)
Original source:
Antoine Bertolotti, et al.
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