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On February 8 , 2022 , the team of Prof.
Jinhao Zhao from the School of Agriculture of Zhejiang University published an online article entitled "pH-Responsive On-Demand Alkaloids Release from Core–Shell ZnO@ZIF-8 Nanosphere for Synergistic Control of Bacterial Wilt" in " ACS Nano " .
Disease" research paper, which established a new method for the acid-controlled release of berberine from the ZnO@ZIF-8 nanocore- shell structure to synergistically and efficiently control tomato bacterial wilt .
Bacterial wilt is a disease caused by Ralstonia solanacearum (Ralstonia solanacearum ) is a devastating soil-borne disease that can seriously damage or even fail the harvest of commercial crops such as tomatoes, potatoes, tobacco and bananas
.
After agricultural streptomycin was banned in China in 2018
Although berberine, a natural product of plant origin, can achieve control effects by inhibiting DNA replication and RNA transcription of R.
solanacearum , it is difficult for berberine to directly penetrate into the cytoplasm, so its efficacy is poor and its onset is slow
Liang Wenlong, a doctoral student at the Agricultural College of Zhejiang University, is the first author of the paper, and Professor Zhao Jinhao is the corresponding author
.
Paper link :https://doi.
org/10.
1021/acsnano.
