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Dysfunctional vascular endothelial cells (ECs) are the pathophysiological basis of various cardiovascular diseases, including atherosclerosi.
To establish the UMGAAV strategy, the research team used a clinical diagnostic ultrasound imaging system with an operating frequency of 4 µMHz, which is also used for clinical carotid ultrasound imagin.
With the exception of the carotid artery, UMGAAV can theoretically be used to deliver foreign genes to all vascular regions that can be monitored by ultrasound imagin.
In conclusion, Pro.
The co-first authors of the paper are postdoctoral fellow Liu Renfa and 2018 doctoral student Qu Shuai from the School of Future Technology of Peking University, Professor Dai Zhifei from the School of Future Technology of Peking University is the corresponding author, and Professor Hanjoong Jo of Georgia Institute of Technology and Emory University also made the research smoot.
