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Figure: One problem with drug therapy is the accompanying adverse effects
Source: (Image courtesy of Okayama University, modified by JST)
Focus on light-sensing proteins
In cancer treatment, it is important to let the cancer cells die
These methods use chemicals that rely on active enzymes or heat to cause necrosis in the body
The means of killing cells can be roughly divided into two categories
The research of Prof.
This is a treatment that is fundamentally different from traditional treatments
First, the researchers synthesized AR3 in human cancer cells and then exposed it to green light at a wavelength of about 550 nanometers (one nanometer equals one billionth of a meter)
Next, they confirmed their method in biology
The AR3 gene must be introduced into cells in order to synthesize AR3
"By using the 'light-induced apoptosis method' we developed, AR3 is synthesized only in human cancer cells and can kill diseased cells without adversely affecting surrounding healthy cells
In addition to Professor Sudou, the research team included Keiichi Kojima, assistant professor at the Department of Medicine, Dentistry and Pharmacy at Okayama University
For a student who doesn't believe the professor's word, this is an amazing achievement
The effectiveness of this approach has now been demonstrated in human cells and in relatively simple animals used for experiments
In this regard, however, a secret experiment by a student is key
"At neutral pH, when using our method, it was necessary to observe longer periods of time
Shin Nakao, a pharmacy student, was the driving force behind these results
with the SDGs as the main guiding principle
Professor Shudou will continue his research on rhodopsin based on photomedicine
It is said that Goethe, the great poet of the 18th and 19th centuries, said before his death: "Mehr Licht! (More light!)" No matter what the original meaning of this sentence is, whenever we hear keywords related to modern technology, such as Renewable energy, photocatalysis, optical communication, will think of this sentence
.
Humans, including those working in the medical field, have ample opportunity to use " Mehr Licht " to solve the problems they face
.
article title
Phototriggered Apoptotic Cell Death (PTA) Using the Light-Driven Outward Proton Pump Rhodopsin Archaerhodopsin-3
