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Among Gram-negative bacteria, including some of the most destructive human pathogens, only two polysaccharide-producing mechanisms
Bacteria not only thrive on sugar as a source of carbon and energy, they also produce and secrete a wide variety of so-called polysaccharides
Polysaccharide export is a major challenge because of the chemical diversity and very large number of molecules
The research team at the Max Planck Institute for Microbiology on Land offers new explanations for these questions
Based on their observations and computational structural biology, the scientists proposed that EpsX and EpsY represent a novel trans-outer membrane polysaccharide output rotor in which a β-barrel protein is explicitly transcomposited as the outer membrane of a bipartric complex with an OPX protein that completely orbits the periplasmic perimeter
This detailed knowledge may open up new ways