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    Home > Biochemistry News > Biotechnology News > A new third mechanism for polysaccharide output

    A new third mechanism for polysaccharide output

    • Last Update: 2022-09-08
    • Source: Internet
    • Author: User
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    Figure: Structural model of a composite OPX/β-barrel transposon in the MYxococcus xanthus EPS pathway, consisting



    Among Gram-negative bacteria, including some of the most destructive human pathogens, only two polysaccharide-producing mechanisms


    Bacteria not only thrive on sugar as a source of carbon and energy, they also produce and secrete a wide variety of so-called polysaccharides


    Polysaccharide export is a major challenge because of the chemical diversity and very large number of molecules


    The research team at the Max Planck Institute for Microbiology on Land offers new explanations for these questions


    Based on their observations and computational structural biology, the scientists proposed that EpsX and EpsY represent a novel trans-outer membrane polysaccharide output rotor in which a β-barrel protein is explicitly transcomposited as the outer membrane of a bipartric complex with an OPX protein that completely orbits the periplasmic perimeter


    This detailed knowledge may open up new ways


    Article title

    Evidence for a Widespread Third System for Bacterial Polysaccharide Export across the Outer Membrane Comprising a Composite OPX/β-Barrel Translocon.


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