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The results of this study are a continuation of the earlier research of the Molecular Biology and Genetics Research Group of Associate Professor Bj?rn Panyella Pedersen
PhD student and first author Laust Bavnhj explained: “STPs are highly dynamic membrane proteins that undergo huge conformational changes during transport
This new study reports two crystal structures of Arabidopsis STP10
Structure and dynamics hand in hand
In collaboration with the team of Professor Birgit schitt from the Department of Chemistry at Aarhus University, the researchers also used the most advanced molecular dynamics simulations, using a variety of independent methods to support the concept of proton binding
Bj?rn Panyella Pedersen said: "Combining these methods, we are not only able to identify the key elements of the transport cycle in STPs, but also provide new evidence for the conserved regulatory mechanism in the sugar porter family
Researchers at Aarhus University have just elucidated the structure of a sugar transport protein that drives sugar transport in plants
Journal Reference :
Laust Bavnhøj, Peter Aasted Paulsen, Jose C.