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Figure: (a) Schematic representation of compressed time-reversal matrix microscopy
Source: Institute of Basic Sciences
Microscopy is an important tool in biomedical research because it enables detailed observation and imaging of tissue
About a year ago, a research team led by Professor CHOI Wonshik from the Centre for Molecular Spectroscopy and Dynamics (CMSD) at the Institute for Basic Sciences (IBS) demonstrated an imaging technique called "reflection matrix microscopy" that combines hardware and the ability to compute advanced adaptive optics
Therefore, this technique becomes a suitable candidate for label-free, non-invasive high-resolution optical imaging inside biological tissues
While the performance of reflection matrix microscopy is amazing, it is not without its drawbacks
In new research published in the journal Light: Science and Applications, the IBS team recently unveiled a new and improved version of their previous AO microscopy technique
To speed up data acquisition, Choi's team used compressed sensing in the context of matrix imaging
In image post-processing, they employed a compressed "time-reversal matrix" and a unique algorithm to identify sample information and aberrations, respectively
Compressed time-reversal matrix imaging enables near real-time AO volumetric imaging
This will open a new avenue for the practical application of matrix imaging in various fields of wave engineering including biomedical imaging
