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Science and Technology Daily, Beijing, May 17 (Reporter Zhang Mengran) A new study published in the journal "Nature Communications" by the Pennington Biomedical Research Center in the United States found that reducing the protein content in the diet will produce effects including prolonging li.
Reducing intake is known to improve health and increase longevity, and there is growing interest in the possibility that reducing protein or amino acid intake could contribute to this beneficial effe.
A few years ago, the Pennington Biomedical Research Center's Neural Signaling Laboratory discovered that the metabolic hormone FGF21 is a key signal that links the body to the brain during times of protein restricti.
Dr Christopher Morrison, professor and director of the Neurosignaling Laboratory, said: "Our data suggest that FGF21 talks to the brain and without this signal the mouse would not 'know' that it was eating a low-protein di.
Studies have shown that a low-protein diet has beneficial metabolic effects in aged mice, improving metabolic health, reducing frailty and extending lifesp.
Previous research has shown that FGF21 acts in the brain to improve the metabolic health of young mice fed a low-protein di.
The researchers hope this work will reveal novel molecular and neural pathways that can be used to improve human heal.
