 Home > Biochemistry News > Biotechnology News > A cross-broad neutralizing epitope targeting the receptor-binding region of the HA head of H1N1 and H5N1 influenza viruses

A cross-broad neutralizing epitope targeting the receptor-binding region of the HA head of H1N1 and H5N1 influenza viruses

 Last Update: 2022-09-07
 Source: Internet
 Author: User

Tags

new view co host

natural anti aging

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Influenza viruses continue to threaten global public health security

In this study, the research team screened for this strain to neutralize cross-subtypes of H1N1 influenza viruses since 1991 (seasonal H1N1 circulating before 2009 and A H1N1 circulating since 2009) and H5N1 avian influenza viruses After the broad-spectrum neutralizing antibody 12H5, in order to explore the clinical application prospect and action mechanism of 12H5, a human-mouse chimeric antibody C12H5, a mouse-derived 12H5 antibody, was constructed, and then systematic research was carried out

(a) Hemagglutination inhibitory activity and micro-neutralizing activity of H1N1 and H5N1 influenza virus cross broad-spectrum neutralizing antibody C12H5; (b) protective effect in animals; (c) epitope structure comparison with the reported broad-spectrum antibody; ( d) H1 and H5 common epitope amino acids

Recently, the research results were published online in Nature Communications as a research paper entitled "Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses"

Paper link:National Research Center for Infectious Disease Diagnostic Reagents and Vaccine Engineering Technology)

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

L-Ascorbate-2-Monophosphate Feed Grade

CAS No.: 109620-90-8

Feed Grade

Potassium Sorbate from reliable manufacturer

CAS No.: 590-00-1

Food Grade

Doxycycline Hydrochloride

CAS No.: 10592-13-9

Pharmaceutical Grade

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.