A breakthrough has been made in the study of reproductive protection of meat

, a team of professors from Northwestern University of Agriculture, Forglin science and technology, conducted an in-depth study of the reproductive protection effects of Chinese medicine meat.
Research team in the early stage of the human environment widely existed environmental endocrine disruptor BPA (often used as plasticizers and widely used in plastic products, with male reproductive development toxicity) as an inducer of male reproductive damage, simulating the pathological and toxic effects of BPA on the body, established a pharmacological model of reproductive damage, based on physiological and pathological models to prove the carnivorous Alcohol can significantly improve sperm activity, sperm count, sperm activity and reduce sperm malformation rate, improve the expression of testosterone-producing enzymes, thereby promoting the secretion of testosterone (T), progesterone-producing hormone (LH), improve androgen levels, effectively inhibit oxidative stress caused by BPA, relieve the reproductive damage caused by BPA.
team went on to confirm that pineal chrysanthemum is the main active substance in the fight against reproductive damage, which can effectively restore sperm count, sperm vitality, increase progesterone production hormone and testosterone levels, and reduce sperm damage.
later mechanism studies revealed that BPA mainly damaged the balance of positive and negative feedback regulation of hypothyroidoid-pituitary gland axis and affected the expression of genes associated with regulating hormones and directly damaged testicular and sperm quality. Pineal chrysanthemum can be distributed into the brain and is the first immunological method to prove that it is targeted at male receptors (Androgen receptor, AR). It is shown that the binding points are Met-894 and Val-713 after the intervention of pine chrysanthemum, which is inhibited by its male subject. The study was published recently in
.
pineal chrysanthemum inhibits the negative feedback regulation path of hormones by inhibiting male subjects from entering the nucleus to initiate gene transcription, while pineal chrysanthemum promotes positive feedback regulation of hormones by stimulating the expression of key enzymes in the synthesis of male hormones, and ultimately promotes the secretion of male hormones, along with an increase in major steroid-producing enzymes, including steroid anabolic proteins (STAR) and steroids. Metabolic enzymes such as CYP11A1, CYP17A1, 3 beta-hydroxysteroid dehydrogenase (HSD3 beta) and 17-beta-hydroxysteroid dehydrogenase (HSD17 beta) indicate that pineal chrysanthemums enhance testosterone biosynthesis, thereby increasing sperm numbers and preventing hypolycemia in rats. Pharmacodynamic analysis showed that pineal chrysanthemums can enter the lower hemispheric brain through the blood-brain barrier, but fail to enter testicular tissue in small amounts, perhaps because of the complexity of the blood testicular barrier, or because the blood-brain barrier contains more cells that swallow small molecules. Pine chrysanthemums increase the synthesis and secretion of LH and T, which in turn boost sperm numbers.
, as a well-known traditional Chinese medicine, has long been considered to nourish the liver and kidneys, lean blood and other effects. This series of studies provides a theoretical basis for the modern cognitive and functional development of meat, and opens up new methods for treating male reproductive disorders. In recent years, the artificial cultivation technology of meat is constantly breakthrough, the area and output of meat cultivation is expanding, but also for the use of the drug in a wide range of medical fields has laid a material foundation. (Source: Science.com)