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    Home > Active Ingredient News > Immunology News > A 30-year-old female patient with elevated leukocytes in the joint effusion and positive HLA-B27, what diagnosis should be considered?

    A 30-year-old female patient with elevated leukocytes in the joint effusion and positive HLA-B27, what diagnosis should be considered?

    • Last Update: 2022-04-30
    • Source: Internet
    • Author: User
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    *For medical professionals to read and reference Xueba Challenge, waiting for you! A 30-year-old female patient had pain during urination 20 days ago, left knee swelling and pain 7 days ago, and right wrist swelling and pain 3 days ago, with obvious tenderness.
    The knee joint effusion was found to have 50,000 WBC/ml, and HLA-B27 was positive
    .

    The diagnosis should first consider A.
    Ankylosing spondylitis B.
    Enteropathic arthritis C.
    Reactive arthritis D.
    Infectious arthritis E.
    Rheumatoid arthritis Previous answer: A Analysis: ① Middle-aged woman, the patient presented with multisystem manifestations Such as oral cavity (stomatitis), skin (congestive erythema), musculoskeletal system (facet joint tenderness), urinary system (proteinuria), blood system (cytopenia) and other lesions, of which the characteristic lesions are facial erythema, combined with patient resistance SSA antibody (+) and anti-double-stranded DNA antibody (+), it can be diagnosed as systemic lupus erythematosus
    .

    ②Anti-double-stranded DNA antibody (+), decreased complement C3, thrombocytopenia, and positive urine protein can all indicate active disease (B, C, D, E are not selected), while anti-SSA antibody (+) indicates connective tissue disease Possibly, it has nothing to do with disease activity, so this topic chooses
    A.

    Link to the previous article: Female patients, oral ulcers, facial erythema, indicators that do not indicate that their disease is active?
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