80750-24-9 has almost the same specificity as streptomycin

English name: Desthiobiotin NHS EsterN-Hydroxysuccinimido dethiobiotinateCAS NO:80750-24-9Molecular formula:C14H21N3O5Molecular weight:311.
34Soluble:Soluble in DMSO, DMF, not soluble in water Content:>95% outside View: White Solid Preservation Method: -20 Light and Moisture Avoidance Product Introduction Desthiobiotin is a monocyclic, sulfur-free biotin, which binds to streptomycin and has almost the same specificity, but has less
affinity compared to biotins (Kd = 1011 and 1015M).

Thus, under mild conditions of competition with free biotin, desulfurization biotins
can be easily and specifically isolated from streptavidin affinity resins.

In pull-down experiments of biological samples, the soft-release properties of desthiobiotins also help to reduce the co-purification of endogenous biotinylated molecules that still bind
to streptococcal peptides under the elution of the free biotin's protein complex of interest.

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