55,000 people study: drinking cancer, but inevitably drink how to do? Doing so reduces the risk.

▎ as a special drink handed down from generation to generation, "wine" has existed in the world for thousands of years and has been an indispensable part of many societies or occasions.in recent years, with the deepening of the research on alcohol, the harm of drinking has gradually revealed.excessive drinking will affect the normal functions of the body such as respiration, heart rate and body temperature, and lead to alcoholism, cardiovascular and cerebrovascular diseases, etc.in addition, studies have shown that even a small amount of alcohol consumption increases the risk of cancer.as a result, many people begin to abstain from alcohol and try not to drink.however, in real life, many people can't help temptation or persuasion, and have to drink some wine.what should I do now? How can the harm of drinking be reduced? A large study, published in the International Journal of cancer, shows that drinking alcohol increases the risk of cancer death, and exercise can reduce the increased risk.source: the International Journal of cancer analyzed data from the England health survey (HSE) and the Scottish Health Survey (SHS), involving 54686 subjects with an average age of 51 years, to assess the relationship between exercise, alcohol consumption, and the risk of cancer death.the data on exercise, drinking and health status of the subjects were analyzed.based on the daily amount of alcohol consumed and the frequency of drinking per week, the researchers calculated the weekly alcohol intake of the subjects and divided them into six groups: never drinking, once drinking, occasionally drinking, drinking within the range recommended by the guidelines (female < 112G / week, male < 168g / week), dangerous drinking (female 112-280g / week, male 168-392g / week), and harmful drinking (female > 280g / week), Male > 392g / week) group.in daily life, the alcohol content can be roughly calculated by "volume (ML) × degree × 0.8g/ml". Taking 500ml 40 ° liquor as an example, it contains about "500ml × 40% × 0.8g / ml = 160g" alcohol.in addition, the researchers also counted the number of deaths caused by alcohol related cancers, including oral cancer, laryngeal cancer, esophageal cancer, liver cancer, colorectal cancer, gastric cancer and female breast cancer.during an average follow-up of 10 years, 2039 subjects died of alcohol-related cancer.Image Source: pixabay adjusted for age, gender, weight, smoking status, fruit and vegetable intake, and found a strong direct correlation between alcohol consumption and increased risk of alcohol-related cancer death.specifically, compared with those who never drank alcohol, those who used to drink alcohol increased the risk of cancer death by 46%; those who drank occasionally increased the risk by 21%; those who drank alcohol within the scope recommended by the guidelines increased the risk of cancer death by 19%; those who drank dangerous alcohol increased the risk by 39%; and those who drank harmful alcohol increased the most, 62%.however, the above-mentioned risks have changed after taking into account the influence of the amount of exercise and time.when the exercise intensity of subjects was lower than the standard of "150 minutes of moderate aerobic exercise per week, or 75 minutes of high intensity aerobic exercise per week", the increased risk of alcohol related cancer death increased. Compared with those who never drank alcohol, those who had drunk alcohol occasionally, drank alcohol occasionally, drank alcohol within the range recommended by the guidelines, dangerous drinking and harmful drinking alcohol had alcohol related cancer death The risk increased by 53%, 28%, 24%, 47% and 64%, respectively. however, the increased risk of alcohol-related cancer death was reduced by 25%, 1%, 8%, 21% and 52%, respectively, when the exercise intensity reached the standard. Image Source: pixabay researchers analyzed that drinking alcohol may increase cancer risk in a variety of ways. for example, alcohol contained in wine and acetaldehyde produced by human digestion of alcohol will damage DNA of healthy cells, increase oxidative stress response, interact with retinoic acid metabolism, increase estrogen concentration and change epigenetic. Exercise can reduce body mass index, oxidative stress, sex hormones and chronic inflammation, improve insulin sensitivity and immune system function, affect gene expression and DNA repair, block alcohol related carcinogens, and prevent alcohol-related cancer and reduce the risk of death. for the study, Dr. ALPA Patel, an epidemiologist with the American Cancer Society, said: "based on the evidence to date, it is best to avoid alcohol consumption and exercise enough. this number is 150-300 minutes of moderate intensity exercise per week, or 75-150 minutes of high-intensity exercise per week to prevent cancer. Photo source: pixabay in short, drinking is harmful to health, and there is no saying that moderate drinking is harmful. after smoking and overweight, drinking alcohol is the third major cancer risk factor that can change. No matter how much alcohol is consumed, no matter how much alcohol is consumed, it is associated with the increased risk of multiple cancers and death. Although exercise can reduce the risk of alcohol-related cancer death, the risk is still higher than that of non drinkers. in daily life, it is better not to drink alcohol. If you drink alcohol, you should exercise enough to reduce the risk as much as possible. of course, it would be better if we could not drink alcohol and exercise enough! Reference materials (slide up and down) [1] yingyu Feng, et al., (2020). Does adequate physical activity attach the associations of alcohol and alcohol related cancer mortality? A pooled study of 54686 British adults. International Journal of cancer, DOI: 10.1002/ijc. 33052. [2] could be active reduce cancer death risk from alcohol?. retrieved Jul 10,2020,from Catherine de Martel, et al.,(2019). Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis. The Lancet Global Health, DOI： Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis. Retrieved Dec 23 ,2019, Note: the purpose of this article is to introduce the progress of medical and health research, not to recommend treatment options. if you need guidance on treatment plan, please go to a regular hospital.