12 pediatric Class 1 new drugs are eye-catching, Hengrui, etc. to grab the first three major direction Nuggets 70 billion market

Children's medicines have a large clinical demand.
Although the current favorable policies to encourage children's drug research and development continue, enterprises still face the problems of large R&D investment and long cycle, difficult drug evaluation, and high production and sales risks
.
For most companies, the development of improved new or generic drugs for children is a more "insurable" choice
.

The list of three batches of drugs that are encouraged to research and develop covers common diseases in many systems such as nerves, cardiovascular, endocrine, blood, and tumors
.
Most of the product regulations have not been declared in China, but have been marketed abroad, and they are all child-friendly dosage forms and specifications that are lacking in China
.
It can be seen from this that specification development, dosage form improvement, and therapeutic field development will become the main directions and urgent needs of children's drug research and development
.

The first is dosage form improvement
.
For products with clear clinical value, significant efficacy and high safety, it is possible to improve the development of special preparations or products suitable for children, such as granules and powders, by improving compliance, overcoming swallowing obstacles, reducing the number/frequency of administration, and improving taste, etc.
, inhalants, patches, oral solutions, chewable tablets and the like
.

Take oseltamivir, the first-line anti-influenza drug, as an example.
The currently marketed dosage forms include capsules and granules.
Among them, the sales scale of granules for children is much larger than that of capsules.
The dosage forms under development include sustained-release tablets and oral tablets.
Disintegrating tablets, suspensions, etc.
, are all child-friendly dosage forms
.

The second is specification development
.
The dosage of drugs used by children of different ages and weights is different, and multiple specifications of the same species have been developed, which are suitable for children of different ages and weights.
On the one hand, it increases the convenience and safety of children's medication, and on the other hand, it is also helpful to open the drug market.

.

The three batches of drugs that are encouraged to research and develop focus on changing the specifications of existing adult drugs.
Some drugs are already sold in other specifications, but the specifications for children are relatively scarce and have clear clinical needs.
This is one of the directions to encourage research and development in the future
.

The last is the development of the treatment field
.
At present, the domestic children's medicine market is mainly used for respiratory, anti-infective, and digestive systems.
The homogeneity of varieties is relatively serious and the competition is high.
However, there is a shortage of drugs in the nervous system, tumor, and cardiovascular diseases, and the market demand is gradually increasing.
Can expand to these therapeutic areas
.

Source: Mi Nei Net Database

Note: Data statistics are as of August 6th, the reporting status is incomplete statistics, welcome to add!